TargetMol

CP-5609

Product Code:
 
TAR-T31065
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T31065-100mg100mgEnquire
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
CP-5609 is a new class of carbapenems with enhanced antimicrobial activity.
CAS:
432038-96-5
Formula:
C23H21N5O6S
Molecular Weight:
495.51
Purity:
0.98
SMILES:
C[C@@H](O)[C@@H]1[C@H]2[C@@H](C)C(=C(N2C1=O)C([O-])=O)c1cn2cnc(C(=O)c3ccc[n+](CC(N)=O)c3)c2s1

Documents

References

1. Hirai Y, Takahata S, Yamada K, Ida T, Maebashi K. Correlation of the antimicrobial activity of ME1036 with its binding affinities to the penicillin-binding proteins from Streptococcus pneumoniae strains. J Antibiot (Tokyo). 2011 Nov;64(11):741-6. doi: 10.1038/ja.2011.76. Epub 2011 Aug 24. PubMed PMID: 21863036. 2. Morrissey I, Biek D, Janes R. ME1036, a novel carbapenem, with enhanced activity against clinical isolates causing bacteraemic community-acquired pneumonia. J Antimicrob Chemother. 2009 Jul;64(1):209-10. doi: 10.1093/jac/dkp163. Epub 2009 May 9. PubMed PMID: 19429928. 3. Yanagihara K, Ohnishi Y, Morinaga Y, Nakamura S, Kurihara S, Seki M, Izumikawa K, Kakeya H, Yamamoto Y, Yamada Y, Kohno S, Kamihira S. Efficacy of ME1036 against meticillin-resistant Staphylococcus aureus and vancomycin-insensitive S. aureus in a model of haematogenous pulmonary infection. Int J Antimicrob Agents. 2008 Nov;32(5):401-4. doi: 10.1016/j.ijantimicag.2008.04.030. Epub 2008 Aug 19. PubMed PMID: 18715761. 4. Fenoll A, Aguilar L, Robledo O, Gim?nez MJ, Granizo JJ, Biek D, Tarrag? D. In vitro activity of ME1036 versus other beta-lactams against penicillin-resistant Streptococcus pneumoniae serotypes exhibiting higher amoxicillin than penicillin MIC. J Antimicrob Chemother. 2008 Nov;62(5):1156-8. doi: 10.1093/jac/dkn314. Epub 2008 Jul 30. PubMed PMID: 18667449.