Leinco Technologies

Anti-Mouse CD3ε (Clone 145-2C11) - Purified in vivo GOLD™ Functional Grade

Product Code:
 
LEI-C1758
Product Group:
 
Primary Antibodies
Host Type:
 
Hamster
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
145-2C11
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Agonism
  • Blocking
  • Depletion
  • Flow Cytometry
  • Functional Study
  • Immunocytochemistry (ICC)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Frozen Section (IHC-F)
  • In Vivo Assay
  • Mass Cytometry (CyTOF)
  • Spatial Biology
  • Western Blot (WB)
Shipping:
 
2-8°C
Storage:
 
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
 

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CodeSizePrice
LEI-C1758-1.0mg1.0 mg£175.00
Quantity:
LEI-C1758-5.0mg5.0 mg£380.00
Quantity:
LEI-C1758-25mg25 mg£1,014.00
Quantity:
LEI-C1758-50mg50 mg£1,556.00
Quantity:
LEI-C1758-100mg100 mg£2,159.00
Quantity:
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This product comes from: US.
Typical lead time: 14-21 working days.
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Further Information

Antigen Distribution:
CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
Concentration:
? 5.0 mg/ml
Conjugate/Tag/Label:
in vivo GOLD™, Purified in vivo Functional Grade
Format:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Immunogen:
H-2Kb-specific mouse cytotoxic T lymphocyte clone BM10-37
Long Description:
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
NCBI Gene:
12501
Purity:
?95% monomer by analytical SEC, >95% by SDS Page
Target:
CD3ε

References

1.) Abdulreda, M.H. et al. (2019) Diabetologia. 63, 237?1250 2.) Skyberg, J. A. et al. (2020) Infection and Immunity. 88: 5. Journal Link