CycLex Total p62 ELISA Kit

sequestosome 1, p60, p62, A170, OSIL, PDB3, ZIP3, p62B/Osi, A170, STAP, OSF-6/Osi, ZIP

The sequstosome1, p62/SQSTM1, is composed of multiple domain, which is Phox/Bem domain1, ZZ-type zinc finger domain, TRAF6 binding domain, LC3-intoracting region (LIR) motif, Keap1-interacting region (KIR), and ubiquitin-associated domain (UBA). Thus p62 plays a multifunctional scaffold protein that organize signal transduction and protein traffic. Additionally, binding to the autophagy regulator Atg8/LC3 through LIR motif and to the polyubiquitinated proteins through UBA domain, p62 is an important mediator for targeting polyubiquitinated proteins to the autophagic degradation system and p62 has a crucial role in the removal of aggregated proteins that are poorly degraded by proteasomes.

This kit is used for the quantitative measurement of human or mouse p62 protein in cell lysate.

Human: 8878 Mouse: 18412

Microplate, 10X Wash Buffer, 50X Phosphatase Inhibitor, 1st Lysis Buffer, 2nd Lysis Buffer, p62 standard, Dilution Buffer, HRP conjugated Detection Antibody, Substrate Reagent, Stop Solution

1.5 - 96 ng/mL

0.154 ng/mL~

Total p62