Elabscience

ATG14 Polyclonal Antibody

Product Code:
 
E-AB-67885
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using ATG14 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of Neuro-2a cells using ATG14 Polyclonal Antibody at 1:1000 dilution.
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Western blot analysis of extracts of various cell lines using ATG14 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Neuro-2a cells using ATG14 Polyclonal Antibody at 1:1000 dilution.

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E-AB-67885-60uL60uL£210.00
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E-AB-67885-120uL120uL£291.00
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E-AB-67885-200uL200uL£431.00
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Further Information

Abbreviation:
ATG14
Background:
Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1. Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK. Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion. Modulates the hepatic lipid metabolism (By similarity.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
42kDa/55kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human ATG14
ObservedMW:
65KDa
Purification method:
Affinity purification
Target Synonym:
ATG14;ATG14L;BARKOR;KIAA0831
UNIProt ID:
Q6ZNE5

Documents