Elabscience

MDM2 Polyclonal Antibody

Product Code:
 
E-AB-31995
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Monkey
  • Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Western Blot analysis of Hela cells using MDM2 Polyclonal Antibody at dilution of 1:2000.
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Western Blot analysis of Hela cells using MDM2 Polyclonal Antibody at dilution of 1:2000.

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E-AB-31995-20uL20uL£125.00
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E-AB-31995-60uL60uL£172.00
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E-AB-31995-120uL120uL£237.00
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E-AB-31995-200uL200uL£344.00
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This product comes from: China.
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Further Information

Abbreviation:
MDM2
Background:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Buffer:
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Calculated MW:
55kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Immunogen:
Synthesized peptide derived from human MDM2 around the non-phosphorylation site of Ser166.
ObservedMW:
90kDa
Purification method:
Affinity purification
Target Synonym:
ACTFS;Double minute 2 protein;E3 ubiquitin-protein ligase Mdm2;Hdm 2;Hdm2;HDMX;MDM 2;MDM2;MDM2 oncogene E3 ubiquitin protein ligase;Mdm2 p53 E3 ubiquitin protein ligase homolog;Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa;MDM2;MDM2BP;Mouse Double Minute 2;MTBP;Murine Double Minute Chromosome 2;Oncoprotein Mdm2;p53 Binding Protein Mdm2;p53-binding protein Mdm2;Ubiquitin protein ligase E3 Mdm2;Ubiquitin protein ligase E3 Mdm2
UNIProt ID:
Q00987

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