Elabscience

LIMK1 Polyclonal Antibody

Product Code:
 
E-AB-13381
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
-20°C
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Immunohistochemistry of paraffin-embedded Human brain tissue using LIMK1 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LIMK1 Polyclonal Antibody at dilution 1:40
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Immunohistochemistry of paraffin-embedded Human brain tissue using LIMK1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LIMK1 Polyclonal Antibody at dilution 1:40

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E-AB-13381-20uL20uL£125.00
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E-AB-13381-60uL60uL£172.00
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E-AB-13381-120uL120uL£237.00
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E-AB-13381-200uL200uL£344.00
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Further Information

Abbreviation:
LIMK1
Background:
There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein is ubiquitously expressed during development and plays a role in many cellular processes associated with cytoskeletal structure.
Buffer:
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Synthetic peptide of human LIMK1
Purification method:
Affinity purification
Target Synonym:
EC 2.7.1.37;LIM domain containing protein kinase;LIM domain kinase 1;LIM kinase;LIM motif containing protein kinase;LIMK 1;LIMK;LIMK-1;limk1;LIMK1
UNIProt ID:
P53667

Documents