Elabscience

TBC1D23 Polyclonal Antibody

Product Code:
 
E-AB-92946
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze/thaw cycles.
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Western blot analysis of extracts of various cell lines using TBC1D23 Polyclonal Antibody at 1:3000 dilution.
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Western blot analysis of extracts of various cell lines using TBC1D23 Polyclonal Antibody at 1:3000 dilution.

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E-AB-92946-60uL60uL£210.00
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E-AB-92946-120uL120uL£291.00
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E-AB-92946-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
TBC1D23
Background:
Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
76kDa/78kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human TBC1D23
ObservedMW:
78kDa
Purification method:
Affinity purification
Target Synonym:
TBC1D23;NS4ATP1
UNIProt ID:
Q9NUY8

Documents