Elabscience

Purified Anti-Human CD22 Antibody[HIB22]

Product Code:
 
E-AB-F1321A
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Mouse
Antibody Isotype:
 
Mouse IgG1, κ
Antibody Clone:
 
HIB22
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Flow Cytometry
Shipping:
 
Ice packs
Storage:
 
Store at 2-8°C. Do not freeze.
 

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CodeSizePrice
E-AB-F1321A-25ug25ug£105.00
Quantity:
E-AB-F1321A-100ug100ug£141.00
Quantity:
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Further Information

Abbreviation:
CD22
Background:
CD22 is < 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Concentration:
0.5 mg/mL
Conjugation:
Unconjugated
GeneID:
933
Target Synonym:
B-cell receptor CD22;Cd22;B-lymphocyte cell adhesion molecule;BL-CAM;Sialic acid-binding Ig-like lectin 2;Siglec-2;T-cell surface antigen Leu-14;CD22;Lyb-8; Siglec2;
UNIProt ID:
P20273
Usage:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is < 2.0 ug per million cells in 100 uL volume. It is recommended that the reagent be titrated for optimal performance for each application.

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