NSJ Bioreagents

CD40 Antibody

Product Code:
 
NSJ-V8350SAF
Product Group:
 
Primary Antibodies
Supplier:
 
NSJ Bioreagents
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2a kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
FGK45.5
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Functional Study
  • Immunofluorescence (IF)
Storage:
 
Store the CD40 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
 

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NSJ-V8350SAF-100UG100 ug£534.00
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Further Information

Application Details:
Functional Studies (order BSA/azide-free format),Flow cytometry: 1-2ug/million cells in 0.1ml,Immunofluorescence: 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4.5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes.
Format:
Purified
Formulation:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Immunogen:
Purified recombinant Mouse CD40 fusion protein was used as the immunogen for the CD40 antibody.
Limitation:
This CD40 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Uniprot #:
P27512

Documents