Mouse Anti-Human TNF-a BioActive Antibody, Clone B-C7, Azide free
Product Code:
855.150.000
855.150.000
Host Type:
Mouse
Mouse
Antibody Isotype:
IgG1
IgG1
Antibody Clonality:
Monoclonal
Monoclonal
Antibody Clone:
B-C7
B-C7
Regulatory Status:
RUO
RUO
Target Species:
Human
Human
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Code | Size | Price |
---|
855.150.000 | 200ug/200ul | £232.00 |
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This product comes from: France.
Typical lead time: 14-21 working days.
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Typical lead time: 14-21 working days.
Contact us for more accurate information.
- Further Information
- References
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Further Information
Activity:
Inhibits TNF? induced cytotoxicity on U937 cells
Antigen:
TNF alpha
Antigen Synonyms:
TNFa
Biological Acivity:
Inhibits TNFα induced cytotoxicity on U937 cells
Conjugate:
Azide free
Format:
Azide free
Hybridoma:
Myeloma X63/AG.8653 x Balb/c spleen cells
Immunisation:
Recombinant human TNF-a
Reactivity:
Human
Research Area:
Cytokines / Growth FactorsInnate Immunity
Specificity:
Recognises both natural and recombinant human TNF-a
References
- Arduise C. et al. J. Immunol.2008; 181(10): 7002-7013.. Tetraspanins Regulate ADAM10-Mediated Cleavage of TNF-{alpha} and Epidermal Growth Factor.. https://www.ncbi.nlm.nih.gov/pubmed/18981120
- Boillot A. et al. Clin Intensive Care1995; 6(2): 52-6.. Pilot clinical trial of an anti-TNF alpha monoclonal antibody for the treatment of septic shock. https://www.ncbi.nlm.nih.gov/pubmed/10150799
- Dyugovskaya L. et al. Am J Respir Crit Care Med.2003; 168(2): 242-9.. Phenotypic and functional characterization of blood gammadelta T cells in sleep apnea. https://www.ncbi.nlm.nih.gov/pubmed/12724124
- Hamacher J. et al. Am J Respir Crit Care Med.2002; 166(5): 651-6.. Tumor necrosis factor-alpha and angiostatin are mediators of endothelial cytotoxicity in bronchoalveolar lavages of patients with acute respiratory distress syndrome.. https://www.ncbi.nlm.nih.gov/pubmed/12204860
- Herve P. et al. Blood1992; 79(12): 3362-8.. Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease. https://www.ncbi.nlm.nih.gov/pubmed/1596576
- Herve P. et al. Bone Marrow Transplant1991; 7 Suppl 2: 149.. Monoclonal anti TNF alpha antibody in the treatment of acute GvHD refractory both to corticosteroids and anti IL-2 R antibody.
- Ida H. et al. J Immunol.1997; 159(5): 2154-60.. CD94 ligation induces apoptosis in a subset of IL-2-stimulated NK cells.. https://www.ncbi.nlm.nih.gov/pubmed/9278302
- Limb G. A. et al. Am J Pathol.2002; 160(5): 1847-55.. Differential expression of matrix metalloproteinases 2 and 9 by glial Muller cells: response to soluble and extracellular matrix-bound tumor necrosis factor-alpha. https://www.ncbi.nlm.nih.gov/pubmed/12000736
- Marfaing-Koka A. et al. Int Immunol.1996; 8(10): 1587-94.. Contrasting effects of IL-4 IL-10 and corticosteroids on RANTES production by human monocytes. https://www.ncbi.nlm.nih.gov/pubmed/8921438
- Mey A. et al. J Leukoc Biol.1997; 61(1): 17-23.. Alteration of dealcylated lipopolysaccharide antagonistic properties by interaction with plasma factors. https://www.ncbi.nlm.nih.gov/pubmed/9000532
- Musey L. et al. J Virol.2003; 77(1): 291-300.. Ontogeny and specificities of mucosal and blood human immunodeficiency virus type 1-specific CD8(+) cytotoxic T lymphocytes. https://www.ncbi.nlm.nih.gov/pubmed/12477834
- Racadot E. et al. Bone Marrow Transplant1995; 15(5): 669-77.. Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients. https://www.ncbi.nlm.nih.gov/pubmed/7670394
- Sabour Alaoui S. et al.PLoS One2012;7(3): e33609. TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus.. https://www.ncbi.nlm.nih.gov/pubmed/22438963
- van Hensbroek M. B. et al. J Infect Dis.1996; 174(5): 1091-7.. The effect of a monoclonal antibody to tumor necrosis factor on survival from childhood cerebral malaria.. https://www.ncbi.nlm.nih.gov/pubmed/8896514
- Venet F. et al. J Immunol.2006; 177(9): 6540-7.. Human CD4+CD25+ regulatory T lymphocytes inhibit lipopolysaccharide-induced monocyte survival through a Fas/Fas ligand-dependent mechanism. https://www.ncbi.nlm.nih.gov/pubmed/17056586