TargetMol

Exarafenib

Product Code:
 
TAR-T63644
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T63644-1mg1mg£176.00
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TAR-T63644-5mg5mg£334.00
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TAR-T63644-10mg10mg£523.00
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TAR-T63644-25mg25mg£783.00
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TAR-T63644-50mg50mg£1,058.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Exarafenib is a potent and orally available pan-RAF inhibitor.Exarafenib has antitumor activity and acts by inhibiting downstream MAPK pathway signaling.Exarafenib is used in cancer research.
CAS:
2639957-39-2
Molecular Weight:
521.58
Pathway:
MAPK
Purity:
0.98
SMILES:
CC=1C(C=2C=C(N=C(N[C@@H](CO)C)C2)N3CCOCC3)=CC(NC(=O)N4C[C@H](CC(F)(F)F)CC4)=CC1
Target:
Raf|p38 MAPK

Documents

References

Miller N, et, al. Antitumor activity of KIN-2787, a next-generation pan-RAF inhibitor, in combination with MEK inhibition in preclinical models of human NRAS mutant melanoma.2022 Jun 2;40(16): e15099.