TargetMol

RMC-6291

Product Code:
 
TAR-T75131
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T75131-5mg5mg£385.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T75131-50mg50mg£1,661.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RMC-6291 is an orally active and covalent inhibitor of KRAS G12C (ON) . RMC-6291 forms a tri-complex within tumor cells between KRAS G12C (ON) and cyclophilin A (CypA). Thus, RMC-6291 prevents KRAS G12C (ON) from signaling via steric blockade of RAS effector binding. RMC-6291 elicits deep and durable suppression on RAS pathway activity in KRAS G12C tumor models [1] .
CAS:
2641998-63-0
Molecular Weight:
1012.26
Purity:
0.98
SMILES:
O=C(N1CCC(C(N(C(C(C)C)C(NC2C(N3NC(CCC3)C(OCC(C)(CC4=C(C5=C(C(C)OC)N=CC=C5)N(CC)C6=CC=C(N7CCOC(C2)C7)C=C46)C)=O)=O)=O)C)=O)(CC1)F)C#CC(C)(C)N(C)C

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