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References
1.Miller-Wideman, M., Makkar, N., tran, M.G.B., et al. Herboxidiene, a new herbicidal substance from Streptomyces chromofuscus A7847. Taxonomy, fermentation, isolation, physico-chemical and biological properties. J. Antibiot. (Tokyo) 45(6), 914-921 (1992).
2.Hasegawa, M., Miura, T., Kuzuya, K., et al. Identification of SAP155 as the target of GEX1A (Herboxidiene), an antitumor natural product. ACS Chem Biol. 6(3), 229-233 (2011).
3.Imaizumi, T., Nakagawa, H., Hori, R., et al. The synthesis and evaluation of the antiproliferative activity of deacidified GEX1A analogues. J Antibiot (Tokyo) 70(5), 675-679 (2017).
4.Jung, H.J., Kim, Y., Shin, J.Y., et al. Antiangiogenic activity of herboxidiene via downregulation of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1?. Arch. Pharm. Res. 38(9), 1728-1735 (2015). [5.] Koguchi, Y., Nishio, M., Kotera, J., et al. Trichostatin A and herboxidiene up-regulate the gene expression of low density lipoprotein receptor. J. Antibiot. (Tokyo). 50(11), 970-971 (1997).