TargetMol

2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium

Product Code:
 
TAR-T83843
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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This product comes from: United States.
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Further Information

Bioactivity:
2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2'(3')-ANT-GTP features an emission peak at 428 nm when excited at 330 nm in aqueous conditions. It functions as an inhibitor of several adenylyl cyclases, notably mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM with manganese), inhibits B. anthracis adenylyl cyclase toxin edema factor (Kis = 4.1 and 13 uM with manganese and magnesium, respectively), and B. pertussis adenylyl cyclase toxin CyaA (Ki = 29 uM with manganese).
Formula:
C17H17N6O15P3.4Na
Molecular Weight:
730.23
Purity:
98%
SMILES:
O[C@@H]1[C@H](OC(C2=C(N)C=CC=C2)=O)[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@H]1N3C(NC(N)=NC4=O)=C4N=C3.O[C@@H]5[C@@H](COP(OP(OP([O-])([O-])=O)([O-])=O)([O-])=O)O[C@@H](N6C(NC(N)=NC7=O)=C7N=C6)[C@@H]5OC(C8=C(N)C=CC=C8)=O.[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

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