TargetMol

Cytogenin

Product Code:
 
TAR-T83916
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T83916-50mg50mgEnquire
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Further Information

Bioactivity:
Cytogenin, a coumarin derivative isolated from S. eurocidicum, exhibits multiple biological effects. It notably diminishes tumor mass in an Ehrlich murine spontaneous adenocarcinoma model with a daily administration of 25 mg/kg. Furthermore, cytogenin (30 and 100 mg/kg per day) counteracts the body weight reduction and the rise in plasma glucose levels induced by streptozotocin, along with reducing pancreatic macrophage infiltration in a diabetes mouse model. Additionally, at a dose of 100 mg/kg per day, it suppresses nitric oxide production triggered by zymosan and LPS, as well as the LPS-induced increase in Il-6 levels in isolated mouse macrophages.
CAS Number:
132971-59-6
Formula:
C11H10O5
Molecular Weight:
222.19
Purity:
98%
SMILES:
O=C1OC(CO)=CC2=C1C(O)=CC(OC)=C2

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