MBL

CDKN1B/p27KIP1 Rabbit pAb

Product Code:
 
MBL-CNA16633P
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Shipping:
 
ice pack : 2 to 4°C temperature range.
Storage:
 
-20°C
 

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CodeSizePrice
MBL-CNA16633P100 uL£442.00
Quantity:
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This product comes from: United States.
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Further Information

Background:
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
Conjugate:
Unconjugated
Formulation (Storage Buffer):
PBS with 0.05% Proclin300, 50% glycerol
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-198 of human CDKN1B/p27KIP1 (NP_004055.1).
Molecular Weight:
22kDa
Purification:
Affinity Purification
Target:
CDKN1B

Documents