MBL

Anti-CD18 (Mouse) Functional Grade

Product Code:
 
MBL-FP20362550
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG2a κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
M18/2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20362550500 ug£568.00
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This product comes from: United States.
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  • Further Information
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Further Information

Background:
The M18/2 monoclonal antibody specifically binds to mouse CD18, a 95kDA integrin beta 2 glycoprotein. CD18 is expressed on all leukocytes with the highest density by NK and T cells. CD18 forms LFA-1 with CD11a, Mac-1 with CD11b and gp150/95 with CD11c. Through these interactions, CD18 has an important role in cellular adhesion. The M18/2 antibody is reported to stimulate Mac-1 and LFA-1 adhesion to their ligands and block tumor cell metastasis.
Concentration:
1 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD18

Documents

References

St?ber, E., et al., Immunity. 2, 507-521 (1995) Akiba, H., et al., J Immunol. 162, 7058-7066 (1999) Calderhead, D. M., et al., J Immunol. 151, 5261-5271 (1993)