MBL

Anti-CD3 (Mouse) mAb Functional Grade

Product Code:
 
MBL-FP20192550
Product Group:
 
Primary Antibodies
Supplier:
 
MBL
Host Type:
 
Rat
Antibody Isotype:
 
IgG2b κ
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
17A2
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Flow Cytometry
  • Functional Study
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
Shipping:
 
4°C
Storage:
 
4°C
 

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MBL-FP20192550500 ug£374.00
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This product comes from: United States.
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Further Information

Background:
The 17A2 monoclonal antibody specifically reacts with the mouse T lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.
Concentration:
2 mg/mL
Formulation:
Phosphate-buffered aqueous solution, ph7.2.
Target:
CD3

Documents

References

Abrams, J. S., et al., Immunol Rev. 127, 5-24 (1992) Cherwinski, H. M., et al., J Exp Med. 166, 1229-1244 (1987) Zhang, Y., et al., J Immunol. 181, 190-196 (2008)