KactusBio Inc.

Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein (MHC-HM408)

Product Code:
 
KAC-MHC-HM408
Product Group:
 
MHC Monomers
Supplier:
 
KactusBio Inc.
Host Type:
 
Human
Regulatory Status:
 
RUO
Shipping:
 
Shipped at ambient temperature.
Storage:
 
-20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
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Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95% 

Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%
The purity of Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer is greater than 95% as determined by SEC-HPLC.

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CodeSizePrice
KAC-MHC-HM408-100UG100UG£313.00
Quantity:
KAC-MHC-HM408-500UG500UG£923.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Background:
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Biotinylated:
no
Description:
Recombinant Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and PLFQVPEPV peptide.
Endotoxin:
Less than 1EU per ug by the LAL method.
Exact Sequence:
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and PLFQVPEPV peptide
Expression System:
HEK293
Form:
Lyophilized
Formulation:
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Gene/Protein ID:
A0A140T913(HLA-A*02:01)&P61769(B2M)&PLFQVPEPV
Molecular Weight:
The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Bis-Tris PAGE result.
Purity:
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Reconstitution:
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Synonyms:
Alpha-fetoprotein; Alpha-1-fetoprotein; Alpha-feto; AFP; HPAFP; AFPD; FETA; MHC
Tag:
C-His-Avi
Target:
HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer

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