Chemodex

Clindamycin hydrochloride

Product Code:
 
CDX-C0324
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +20°C. Long term: +4°C
Chemical Structure

Chemical Structure 

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CodeSizePrice
CDX-C0324-G01010 g£75.00
Quantity:
CDX-C0324-G02525 g£145.00
Quantity:
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This product comes from: Switzerland.
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  • Further Information
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Further Information

Appearance:
White to off-white powder.
CAS:
21462-39-5
Description:
Clindamycin hydrochloride is a semi-synthetic, lincosamide antibiotic that is prepared from lincomycin. It inhibits bacterial protein synthesis by hydrogen bond interactions with the 23S rRNA component of the 50S ribosomal subunit thus inducing dissociation of the peptidyl-t-RNA complex. It has antibacterial activity against Gram-positive cocci and antiprotozoal activity against Taxoplasma. Clindamycin is used to study bacterial infections, such as group B streptococcal disease, bacterial resistance and plasma protein binding and used to study bacterial protein synthesis.
EClass:
32160000
Form:
solid
GHS:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H317-H319-H362
InChi:
InChI=1S/C18H33ClN2O5S.ClH/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4;/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25);1H/t9-,10+,11-,12+,13-,14+,15+,16+,18+;/m0./s1
InChi Key:
AUODDLQVRAJAJM-XJQDNNTCSA-N
MDL:
MFCD07793327
Molecular Formula:
C18H33ClN2O5S . HCl
Molecular Weight:
461.44
Package Type:
Vial
Precautions:
P260-P263-P280-P302 + P352-P305 + P351 + P338-P308 + P313
Purity:
>97% (TLC)
Signal word:
Warning
SMILES:
O[C@H]1[C@@H](SC)O[C@]([H])([C@@H]([C@H](C)Cl)NC([C@]2([H])C[C@@H](CCC)CN2C)=O)[C@H](O)[C@@H]1O.Cl
Solubility:
Soluble in water (50mg/ml) or DMSO (50mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

Documents

References

(1) M. Smieja; Can. J. Inf. Dis. Med. Microbiol. 9, 22 (1998) | (2) W.S. Champney; Curr. Drug Targets Infect. Disord. 1, 19 (2001) | (3) B. Lell & P.G. Kremsner; Antimicr. Agents Chemother. 46, 2315 (2002) | (4) J. Spizek & T. Rezanka; Appl. Microbiol. Biotech. 64, 455 (2004) | (5) J. Spizek, et al.; Adv. Appl. Microbiol. 56, 121 (2004) | (6) E.S.R. Darley & A.P. MacGowan; J. Antimicrob. Chemother. 53, 928 (2004) | (7) D.N. Wilson; Nat. Rev. Microbiol. 12, 35 (2014)