Storage:
Short term: +20°C. Long term: +4°C
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
White to off-white powder.
50-02-2
Dexamethasone is a potent anti-inflammatory and immunosuppressive agent useful in a variety of inflammatory and autoimmune conditions. This synthetic glucocorticoid acts as an agonist of human glucocorticoid receptor (GR) and binds with a higher affinity than the natural ligand cortisol. Through GR activation, dexamethasone has both transactivating and transrepressing effects on gene expression, resulting in anti-inflammatory properties. The anti-inflammatory effects are complex, but primarily via inhibition of inflammatory cells and suppression of expression of inflammatory mediators.
32160000
solid
GHS08
Protect from light and moisture.
H360FD
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
UREBDLICKHMUKA-CXSFZGCWSA-N
MFCD00064136
C22H29FO5
392.46
Vial
P201-P202-P280-P308 + P313-P405-P501
>98% (HPLC)
Danger
O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(CO)=O)=C1
Soluble in DMSO (25mg/ml), ethanol (20mg/ml) or chloroform.
Synthetic
Non-hazardous
12352200
Stable for at least 2 years after receipt when stored at +4°C.
