Storage:
Short term: +20°C. Long term: +20°C
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This product comes from:
Switzerland.
Typical lead time:
7-10 working days.
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Further Information
White to off-white powder.
50-23-7
Hydrocortisone is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). Hydrocortisone has three times the anti-inflammatory potency of corticosterone but much lower Na+ retention potency. It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor. Hydrocortisone plays a role in the regulation of metabolism, electrolyte balance, water balance, and the body's stress response. Hydrocortisone production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson's disease. It has been utilized in research to investigate the impact of inflammation and stress on cellular processes.
32160000
solid
GHS08
Protect from light and moisture.
H360Df-H373
InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
JYGXADMDTFJGBT-VWUMJDOOSA-N
MFCD00011654
C21H30O5
362.46
Vial
P202-P260-P280-P308 + P313-P405-P501
>98% (HPLC)
Danger
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])CC[C@]4(O)C(CO)=O)=C1
Soluble in DMSO (20mg/ml).
Synthetic
Non-hazardous
12352200
Stable for at least 2 years after receipt when stored at RT.