Chemodex

4-Methylumbelliferyl alpha-L-fucopyranoside

Product Code:
 
CDX-M0587
Product Group:
 
Dyes, Stains, and Probes
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
Ambient
Storage:
 
Short term: +4°C. Long term: -20°C
Chemical Structure

Chemical Structure 

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CDX-M0587-M01010 mg£301.00
Quantity:
CDX-M0587-M02525 mg£557.00
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This product comes from: Switzerland.
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  • Further Information
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Further Information

Appearance:
White solid.
CAS:
54322-38-2
Description:
4-Methylumbelliferyl-alpha-L-fucopyranoside is a non-fluorescent but fluorogenic substrate for alpha-L-fucosidase (FUCA1) yielding a blue fluorescent solution. It is a fluorogenic MU substrate for detecting alpha-L-fucosidase in cell extracts and purified enzyme preparations using a fluorescence microplate reader or fluorometer. Hydrolysis of 4-Methylumbelliferyl-alpha-L-fucopyranoside releases the fluorescent product 4-MU. Spectral Data. lambdaEx/lambdaEm= 360/450 nm (cleaved product, pH-dependent).
EClass:
32160000
Form:
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C16H18O7/c1-7-5-12(17)23-11-6-9(3-4-10(7)11)22-16-15(20)14(19)13(18)8(2)21-16/h3-6,8,13-16,18-20H,1-2H3/t8-,13+,14+,15-,16-/m0/s1
InChi Key:
CQKHENXHLAUMBH-CRLRYRHBSA-N
MDL:
MFCD00051218
Molecular Formula:
C16H18O7
Molecular Weight:
322.31
Package Type:
Vial
Purity:
>98% (HPLC)
SMILES:
C[C@@H]1O[C@@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)[C@@H](O)[C@H](O)[C@@H]1O
Solubility:
Soluble in DMF (20mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

Documents

References

(1) D. Robinson & R. Thorpe; Clin. Chim. Acta 55, 65 (1974) | (2) J.A. Alhadeff, et al.; Clin. Chim. Acta 57, 307 (1974) | (3) R.L. Hopfer, et al.; Biochem. J. 266, 491 (1990) | (4) G.Y. Wiederschain, et al.; Carbohydr. Res. 224, 255 (1992) | (5) H. Takeshita, et al.; Hum. Genet. 94, 224 (1994) | (6) S. Khunsook, et al.; Mol. Hum. Reprod. 8, 221 (2002) | (7) C. Li, et al.; World J. Gastroenterol. 12, 3770 (2006)