Progranulin (human) ELISA Kit

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration: R. Ghidoni, et al.; Neurology 71, 1235 (2008) | Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia: R. Rademakers, et al.; Hum. Mol. Genet. 17, 3631 (2008) | Serum progranulin concentrations may be associated with macrophage Infiltration into omental adipose tissue: B.S. Youn, et al.; Diabetes 58, 627 (2009) | Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members: N. Finch, et al.; Brain 132, 583 (2009) | Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease: M. Carecchio, et al.; J. Neurol. Sci. 287, 291 (2009) | Cerebrospinal fluid progranulin levels in patients with different multiple sclerosis subtypes: M. De Riz, et al.; Neurosci. Lett. 469, 234 (2010) | Low Serum Progranulin Predicts the Presence of Mutations: A Prospective Study: E.C. Schofield, et al.; J. Alzheimers Dis. 22, 981 (2010) | A Novel Progranulin Mutation Causing Frontotemporal Lobar Degeneration with Heterogeneous Phenotypic Expression: G. Rossi, et al.; J. Alzheimers Dis. 23, 7 (2010) | Pathogenic cysteine mutations affect progranulin function and production of mature granulins: J. Wang, et al.; J. Neurochem. 112, 1305 (2010) | Microglial upregulation of progranulin as a marker of motor neuron degeneration: T. Philips, et al.; J. Neuropathol. Exp. Neurol. 69, 1191 (2010) | A novel progranulin mutation causing frontotemporal lobar degeneration with heterogeneous phenotypic expression: G. Rossi, et al.; J. Alzheimers Dis. 23, 7 (2011) | rs5848 polymorphism and serum progranulin level: G.Y. Hsiung, et al.; J. Neurol. Sci. 300, 28 (2011) | Association of TMEM106B Gene Polymorphism With Age at Onset in Granulin Mutation Carriers and Plasma Granulin Protein Levels: C. Cruchaga, et al.; Arch. Neurol. 68, 581 2011 | Progranulin expression in brain tissue and cerebrospinal fluid levels in multiple sclerosis: M. Vercellino, et al.; Mult. Scler. 17, 1194 (2011) | Soluble Beta-amyloid precursor protein is related to disease progression in amyotrophic lateral sclerosis: Steinacker, et al.; PLoS One. 6, e23600 (2011) | Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients: P. Boss?, et al.; J. Neuroinflammation 8, 65 (2011) | Mucosal Progranulin expression is induced by H. pylori, but independent of Secretory Leukocyte Protease Inhibitor (SLPI) expression: T. Wex, et al.; BMC Gastroenterol. 11, 63 (2011) | Phenotypic heterogeneity of the GRN Asp22fs mutation in a large Italian kindred: A.M. Pietroboni, et al.; J. Alzheimers Dis. 24, 253 (2011) | Progranulin Genetic Screening in Frontotemporal Lobar Degeneration Patients From Central Italy: S. Bagnoli, et al.; Cell Mol. Neurobiol. 32, 13 (2011) | Optimal Plasma Progranulin Cutoff Value for Predicting Null Progranulin Mutations in Neurodegenerative Diseases: A Multicenter Italian Study: R. Ghidoni, et al.; Neurodegener. Dis. 9, 121 (2012) | Prevalence of frontotemporal lobar degeneration in an isolated population: the Vallecamonica study: N. Gilberti, et al.; Neurol. Sci. 33, 899 (2012) | Granulin mutation drives brain damage and reorganization from preclinical to symptomatic FTLD: B. Borroni, et al.; Neurobiol. Aging. 33, 2506 (2012) | Mining the Gastric Cancer Secretome: Identification of GRN as a Potential Diagnostic Marker for Early Gastric Cancer: H. Loei, et al.; J. Proteome Res. 11, 1759 (2012) | Two patterns of adipokine and other biomarker dynamics in a long-term weight loss intervention: M. Blueher, et al.; Diabetes Care 35, 342 (2012) | Expansion mutation in C9ORF72 does not influence plasma progranulin levels in frontotemporal dementia: O. Dols-Icardo, et al.; Neurobiol. Aging 33, 1851 (2012) | Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage: K.R. Smith, et al.; Am. J. Hum. Genet. 90, 1102 (2012) | C9ORF72 repeat expansions and other FTD gene mutations in a clinical AD patient series from Mayo Clinic: A. Wojtas, et al.; Am. J. Neurodegener. Dis. 1, 107 (2012) | Progranulin as a Prognostic Biomarker for Breast Cancer Recurrence in Patients Who Had Hormone Receptor-Positive Tumors: A Cohort Study: D.H. Koo, et al.; PLoS One 7, e39880 (2012) | Clinical, Neuropathological, and Genetic Characteristics of the Novel IVS9+1delG GRN Mutation in a Patient with Frontotemporal Dementia: R. Taipaa, et al.; J. Alzheimers Dis. 30, 83 (2012) | Early Onset Behavioral Variant Frontotemporal Dementia due to the C9ORF72 Hexanucleotide Repeat Expansion: Psychiatric Clinical Presentations: A. Arighi, et al.; J. Alzheimers Dis. 31, 447 (2012) | Serum Progranulin Levels in Patients with Frontotemporal Lobar Degeneration and Alzheimer's Disease: Detection of GRN Mutations in a Spanish Cohort: A. Antonell, et al.; J. Alzheimers Dis. 31, 581 (2012) | Progranulin as a prognostic biomarker for breast cancer recurrence in patients who had hormone receptor-positive tumors: a cohort study: D.H. Koo, et al.; PLoS One 7, e39880 (2012) | Circulating Progranulin Levels in Women with Gestational Diabetes Mellitus and Healthy Controls During and After Pregnancy: J. Todoric, et al.; Eur. J. Endocrinol. 167, 561 (2012) | Epidemiology and genetics of frontotemporal dementia: a door-to-door survey in Southern Italy: L. Bernardi, et al.; Neurobiol. Aging 33, 2948 (2012) | TMEM106B, the risk gene for frontotemporal dementia, is regulated by the microRNA-132/212 cluster and affects progranulin pathways: A.S. Chen-Plotkin, et al.; J. Neurosci. 32, 11213 (2012) | Alteration in cell cycle-related proteins in lymphoblasts from carriers of the c.709-1G>A PGRN mutation associated with FTLD-TDP dementia: C. Alquezara, et al.; Neurobiol. Aging 33,429.e7 (2012) | Pooled-DNA sequencing identifies novel causative variants in PSEN1, GRN and MAPT in a clinical early-onset and familial Alzheimer's disease Ibero-American cohort: S.C. Jin, et al.; Alzheimers Res. Ther. 4, 34 (2012) | Structural Brain Signature of FTLD Driven by Granulin Mutation: M. Bozzali, et al.; J. Alzheimers Dis. 33, 483 (2012) | Progranulin antibodies in autoimmune diseases: L. Thurner, et al.; J. Autoimmun. 42, 29 (2013) | Progranulin gene (GRN) promoter methylation is increased in patients with sporadic frontotemporal lobar degeneration: D. Galimberti, et al.; Neurol. Sci. 34, 899 (2013) | GRN Variant rs5848 Reduces Plasma and Brain Levels of Granulin in Alzheimer's Disease Patients: A. Kamalainen, et al.; J. Alzheimers Dis. 33, 23 (2013) | Implication of Progranulin and C1q/TNF-Related Protein-3 (CTRP3) on Inflammation and Atherosclerosis in Subjects with or without Metabolic Syndrome: H.J. Yoo, et al.; PLOS One 8, e55744 (2013) | Screening for progranulin mutations by serum protein dosage in common neurodegenerative disorders: E. Rodriguez-Rodriguez, et al.; Parkinson. Rel. Disord. 19, 768 (2013) | Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration: H.-H. Chiang, et al.; Eur. J. Hum. Gen. 21, 1260 (2013) | Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis: L. Thurner, et al.; Arthritis Res. Ther. 15, R211 (2013) | Crosstalk between circulating peroxisome proliferator-activated receptor gamma, adipokines and metabolic syndrome in obese subjects: K. Mirzaei, et al.; Diabetol. Metabol. Syndr. 5, 79 (2013) | Implications of C1q/TNF-related protein-3 (CTRP-3) and progranulin in patients with acute coronary syndrome and stable angina pectoris: K.M. Choi, et al.; Cardiovasc. Diabetol. 13, 14 (2014) | Circulating progranulin level is associated with visceral fat and elevated liver enzymes: Significance of serum progranulin as a useful marker for liver dysfunction: Y. Tanaka, et al.; Endocr. J. 61, 1191 (2014) | Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation: G. Flehmig, et al.; PLoS One 9, e99785 (2014) | Progranulin Is Associated with Disease Activity in Patients with Rheumatoid Arthritis: L.A. Cerezo, et al.; Mediators Inflamm. 2015, 740357 (2015) | Progranulin as a candidate biomarker for therapeutic trial in patients with ALS and FTLD: E. Feneberg, et al.; J. Neural. Transm. 123, 289 (2016) | Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study: J. Johnson, et al.; Clin. Rheumatol. 36, 507 (2016) | Reduced miR-659-3p levels correlate with progranulin increase in hypoxic conditions: implications for frontotemporal dementia: P. Piscopo, et al.; Front. Mol. Neurosci. 9, 31 (2016) | Prosaposin is a regulator of progranulin levels and oligomerization: A.M. Nicholson, et al.; Nat. Commun. 7, 11992 (2016) | Missense mutations in progranulin gene associated with frontotemporal lobar degeneration: study of pathogenetic features: C.M. Karch, et al.; Neurobiol. Aging 38, 215.e1 (2016) | Progranulin mutation analysis: Identification of one novel mutation in exon 12 associated with frontotemporal dementia: P.M. Aswathy, et al.; Neurobiol. Aging 39, 218.e1 (2016) | Diagnostic value of cerebrospinal fluid tau, neurofilament, and progranulin in definite frontotemporal lobar degeneration: J. Goossens, et al.; Alzheimer's Res. Ther. 10, (2018) | Plasma progranulin levels for frontotemporal dementia in clinical practice: a 10-year French experience: L. Sellami, et al.; Neurobiol. Aging 91, 167.e1 (2020) | Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression: P.F. Cheung, et al.; bioRxiv (Preprint) (2021) | Autopsy-diagnosed neurodegenerative dementia cases support the use of cerebrospinal fluid protein biomarkers in the diagnostic work-up: M. Bruzova, et al.; Nature Sci. Rep. 11, 10837 (2021)