Product Code:
AG-CN2-0006
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This product comes from:
Switzerland.
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7-10 working days.
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Further Information
Alternate Names/Synonyms:
2,3,6,8-Tetrahydroxy-1-methylxanthone
Yellowish solid.
548740-86-9
32160000
solid
Protect from light.
InChI=1S/C14H10O6/c1-5-11-10(4-8(17)13(5)18)20-9-3-6(15)2-7(16)12(9)14(11)19/h2-4,15-18H,1H3
YPBXGIBBOZOVPM-UHFFFAOYSA-N
Chemical. CAS: 548740-86-9. Formula: C14H10O6. MW: 274.1. Isolated from marine fungus Arthrinium sp. Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.
MFCD19381839
C14H10O6
274.1
Vial
Antiproliferative agent against selected cancer cell lines. Inhibits protein kinases ALK, ARK5, Aurora-B, AXL, FAK, IGF1-R, MET, PIM1, PLK1, PRK1, SRC, and VEGF-R2 with IC50 values between 0.3 and 75.7µM, most probably contributing to the antiproliferative activity. Shown to inhibit VEGF-A dependent endothelial cells sprouting with IC50 value of 1.8µM corresponding to its in vitro inhibitory activity against VEGF-R2 protein kinase (IC50=0.8µM). Lck (p56lck; lymphocyte specific tyrosine kinase) inhibitor. Antioxidant. DPPH radical scavenger.
>97% (HPLC)
[H]C1=C(O)C(O)=C(C)C2=C1OC1=C(C(O)=CC(O)=C1)C2=O
Soluble in 100% ethanol or DMSO.
Isolated from marine fungus Arthrinium sp.
Non-hazardous
Natural Products/Extracts
12352200
Stable for at least 2 years after receipt when stored at -20°C.