Further Information
MFSD1 Antibody: SMAP4, SMAP4, UG0581B09, Major facilitator superfamily domain-containing protein 1, Smooth muscle cell-associated protein 4, SMAP-4
MFSD1 antibody can be used for detection of MFSD1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.
MFSD1 Antibody: Multidrug transporters, such as MFSD1, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that include uniporters, symporters, and antiporters. Members of this family are found in all living organisms and are highly represented in bacteria. MFS members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFS have provided important insight into the mechanism underlying multidrug transport. MFSD1 is still poorly understood.
- Fluman N and Bibi E. Bacterial multidrug transport through the lens of the major facilitator superfamily. Biochim. Biophys. Acta.2009; 1794:738-47.
- Law CJ, Maloney PC, and Wang DN. Ins and outs of major facilitator superfamily antiporters. Annu. Rev. Microbiol.2008; 62:289-305.
- Saidijam M, Benedetti G, Ren Q, et al. Microbial drug efflux proteins of the major facilitator superfamily. Curr. Drug Targets2006; 7:793-811.
MFSD1 Antibody is supplied in PBS containing 0.02% sodium azide.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (78%)
MFSD1 antibody was raised against an 18 amino acid synthetic peptide near the center of human MFSD1.
The immunogen is located within amino acids 220 - 270 of MFSD1.
64747
major facilitator superfamily domain containing 1
MFSD1
Homo sapiens
Liquid
NP_073573
269847416
MFSD1 Antibody is affinity chromatography purified via peptide column.
Homeostasis
Q9H3U5
Optimal dilutions for each application to be determined by the researcher.