ProSci

ZBTB9 Antibody

Product Code:
 
PSI-6131
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
1 / 3
Western blot analysis of ZBTB9 in mouse heart tissue lysate with ZBTB9 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
2 / 3
Immunohistochemistry of ZBTB9 in mouse heart tissue with ZBTB9 antibody at 2.5 μg/mL.
3 / 3
Immunofluorescence of ZBTB9 in mouse heart tissue with ZBTB9 antibody at 20 μg/mL.
❮❯

Western blot analysis of ZBTB9 in mouse heart tissue lysate with ZBTB9 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of ZBTB9 in mouse heart tissue with ZBTB9 antibody at 2.5 μg/mL.
Immunofluorescence of ZBTB9 in mouse heart tissue with ZBTB9 antibody at 20 μg/mL.

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CodeSizePrice
PSI-6131-0.02mg0.02mg£150.00
Quantity:
PSI-6131-0.1mg0.1mg£449.00
Quantity:
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Further Information

Additional Names:
ZBTB9 Antibody: ZNF919, Zinc finger and BTB domain-containing protein 9
Application Note:
ZBTB9 antibody can be used for detection of ZBTB9 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL. For immunofluorescence start at 5 μg/mL.

Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
ZBTB9 Antibody: The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB9, also known as ZNF919, is present in multiple tissues, and is highly expressed in the cytoplasm of the placenta. While little is known about ZBTB9, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Another ZBTB proteins, ZBTB7A, has been implicated as a proto-oncogene whose overexpression contributes to malignancy in breast cancer, suggesting that ZBTB9 may act as a transcriptional repressor or be involved in tumorigenesis.
Background References:
  • Filion GJP, Zhenilo S, Salozhin S, et al. A family of zinc finger proteins that bind methylated DNA and repress transcription. Mol. Cell. Biol. 2006; 26:169-81.
  • Qu H, Qu D, Chen F, et al. ZBTB7 overexpression contributes to malignancy in breast cancer. Cancer Invest. 2010; 28:672-8.
Buffer:
ZBTB9 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
ZBTB9 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human ZBTB9.

The immunogen is located within the first 50 amino acids of ZBTB9.
NCBI Gene ID #:
221504
NCBI Official Name:
zinc finger and BTB domain containing 9
NCBI Official Symbol:
ZBTB9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_689948
Protein GI Number:
23308693
Purification:
ZBTB9 Antibody is affinity chromatography purified via peptide column.
Research Area:
Cancer,Cell Cycle
SPECIFICITY:
This antibody is predicted to not cross-react with other ZBTB protein family members.
Swissprot #:
Q96C00
User NOte:
Optimal dilutions for each application to be determined by the researcher.