Further Information
H3/b, H3FB, ERBB, ERBB1, HER1, H3/a, H3/c, H3/d, H3/f, H3/h
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- Dai J, et al. (2005) Genes Dev 19 (4): 472-488. Yih LH, et al. (2005) Carcinogenesis 26 (1): 53-63.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Histone H3.1 (Phospho-Ser10) antibody was raised against a peptide sequence around phosphorylation site of serine 10 (R-K-S (p) -T-G) derived from Human Histone H3.1.
Phospho-Specific
8351
histone cluster 1, H3d
HIST1H3D
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
NP_003521.2
21071021
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific
This antibody detects endogenous level of Histone H3.1 onlywhen phosphorylated at serine 10.
P68431