Further Information
TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG
Western Blot: 1:500~1:1000
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
- Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.
79058
alveolar soft part sarcoma chromosome region, candidate 1
ASPSCR1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
70 - 75 kDa
NP_076988.1
13129078
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous levels of total ASPSCR1 protein.
Q9BZE9