ProSci

TFE3 Antibody

Product Code:
 
PSI-79-650
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from 293 cells using TFE3 Antibody.
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Western blot analysis of lysed extracts from 293 cells using TFE3 Antibody.

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PSI-79-650-0.1mg0.1mg£481.00
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Further Information

Additional Names:
TFEA, RCCP2, RCCX1, bHLHe33, MAPTL, MTBT1, TAU, BHLHE33, TFEA
Application Note:
Western Blot: 1:500~1:1000
Background:
Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.
Background References:
  • Clark J., Lu Y. -J., Sidhar S. K., Parker C., Gill S., Oncogene 15:2233-2239 (1997) Weterman M. A. J., Wilbrink M., Proc. Natl. Acad. Sci. U. S. A. 93:15294-15298 (1996)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TFE3 antibody was raised against a peptide sequence around aa.303~307 (L-D-V-Y-S) derived from Human TFE3.
NCBI Gene ID #:
7030
NCBI Official Name:
transcription factor binding to IGHM enhancer 3
NCBI Official Symbol:
TFE3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
70 kDa
Protein Accession #:
NP_006512.2
Protein GI Number:
8659574
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous levels of total TFE3 protein.
Swissprot #:
P19532