Antibody Clonality:
Polyclonal
Target Species:- Canine (dog)
- Human
- Mouse
- Rat
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNQ2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
KCNQ2, EBN, BFNC, EBN1, ENB1, BFNS1, EIEE7, HNSPC, KV7.2, KCNA11, KVEBN1
KCNQ2 antibody can be used for detection of KCNQ2 by ELISA at 1:62500. KCNQ2 antibody can be used for detection of KCNQ2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by the KCNQ2 gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1).
- Tang, B., et al., (2004) J. Neurol. Sci. 221 (1-2), 31-34.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNQ2.
3785
potassium voltage-gated channel, KQT-like subfamily, member 2
KCNQ2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
NP_742107
26051268
Antibody is purified by protein A chromatography method.
Membrane ,Neuroscience
Q5VYU0
Optimal dilutions for each application to be determined by the researcher.