Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.
1 / 2
2 / 2
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United States.
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Further Information
HB16, CREB2, TREB7, CREB-2, CRE-BP1, ERBB, ERBB1, HER1, CREBP1
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
- Sevilla A, et al. (2004) J Biol Chem. 279 (26): 27458-27465. Waetzig G H, et al. (2002) J Immunol. 168 (10): 5342-5351. Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089. Gupta S, et al. (1995) Science. 267: 389-393. Van Dam H, et al. (1995) EMBO J. 14 (8): 1798-1811.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
ATF2 (Phospho-Thr71 or 53) antibody was raised against a peptide sequence around phosphorylation site of threonine 71 or 53 (T-P-T (p) -P-T) derived from Human ATF2.
Phospho-Specific
1386
activating transcription factor 2
ATF2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
65 - 75 kDa
NP_001871.2
22538422
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Phospho-Specific
This antibody detects endogenous level of ATF-2 only when phosphorylated at threonine 71 or 53.
P15336