ProSci

CKit Monoclonal Antibody

Product Code:
 
PSI-32-138
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
8D7B4
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
C-Kit monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis using C - kit monoclonal antibody against truncated C - kit recombinant protein
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Western blot analysis using C - kit monoclonal antibody against truncated C - kit recombinant protein

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PSI-32-138-0.1mL0.1mL£560.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117
Application Note:
Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.
Background:
C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
Background References:
  • Mojica WD et.alHistopathology. 2005 Nov;47(5):517-22.
  • Tong WD et.alInt J Colorectal Dis. 2005 Jul;20(4):363-7. Epub 2005 Feb 2.
  • Nakai Y et.alBiochem Biophys Res Commun. 2005 Nov 11;337(1):289-96.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
3815
NCBI Official Name:
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
NCBI Official Symbol:
KIT
NCBI Organism:
Homo sapiens
Protein Accession #:
P10721
Protein GI Number:
125472
Purification:
Antibody is purified by protein A affinity chromatography.
Research Area:
Innate Immunity
Swissprot #:
P10721
User NOte:
Optimal dilutions for each application to be determined by the researcher.