ProSci

SNCG Monoclonal Antibody

Product Code:
 
PSI-32-216
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG1
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
1H10D2
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
SNCG (breast cancer-specific protein 1) monoclonal antibody can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures
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Western blot analysis using SNCG monoclonal antibody against truncated SNCG recombinant protein.
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Western blot analysis using SNCG monoclonal antibody against truncated SNCG recombinant protein.

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PSI-32-216-0.1mg0.1mg£524.00
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Further Information

Additional Names:
BCSG1, PERSYN, PRSN, Breast cancer-specific gene 1 protein, SR, BCSG1
Application Note:
Western Blot:1:500 - 1:2,000
IHC(P):1:500 - 1:2,000
IHC(F):1:500 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Background:
SNCG(also designated gamma-synuclein or breast cancer-specific protein 1),with 127-amino acid protein(about 14 kDa), belongs to the synuclein family, which also includes alpha- and beta- synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Background References:
  • Haiyan Liu, Wei Liu, Yinwei Wu. Cancer Res. 2005 Sep 1;65(17):7635-43.
  • rina Surgucheva , Belinda McMahon , Andrei Surguchov. Cell Motil Cytoskeleton. 2006 May 26.
Buffer:
Ascitic fluid containing 0.03% sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3).
NCBI Gene ID #:
6623
NCBI Official Name:
synuclein, gamma (breast cancer-specific protein 1)
NCBI Official Symbol:
SNCG
NCBI Organism:
Homo sapiens
Protein Accession #:
O76070
Protein GI Number:
90110074
Purification:
Antibody is purified by protein A affinity chromatography.
Swissprot #:
O76070
User NOte:
Optimal dilutions for each application to be determined by the researcher.