MAPK1/3 (phospho Tyr205/222) Antibody
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store antibody at -20°C for up to one year.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
ERK, ERT1, MAPK 1, MAPK2, ERK2
Western Blot: 1:500~1:1000
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
- Owaki H., Biochem. Biophys. Res. Commun. 182:1416-1422(1992).
- Dunham I., Nature 402:489-495(1999).
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
MAPK1/3 (phospho Tyr205/222) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 205/222 (K-G-Y (p)-T-K) derived from Human MAPK1/3 .
Phospho-Specific
5594/5595
mitogen-activated protein kinase 1, mitogen-activated protein kinase 3
MAPK1, MAPK3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
NP_002736.3
66932916
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Phospho-Specific
The antibody detects endogenous levels of MAPK1/3 only when phosphorylated at tyrosine 205/222.
P28482/P27361