Further Information
Matrix metalloproteinase-26, MMP-26, 3424-, Endometase, Matrilysin-2, MMP26
For WB starting dilution is: 1:1000
Proteins of the matrix metalloproteinase (MMP) family are
involved in the breakdown of extracellular matrix in normal
physiological processes, such as embryonic development,
reproduction, and tissue remodeling, as well as in disease
processes, such as arthritis and metastasis. Most MMP's are
secreted as inactive proproteins which are activated when cleaved
by extracellular proteinases. The encoded protein degrades type IV
collagen, fibronectin, fibrinogen, casein, vitronectin, alpha
1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth
factor-binding protein 1, and activates MMP9 by cleavage. The
protein differs from most MMP family members in that it lacks a
conserved C-terminal protein domain.
- de Amorim, R.F., et al. Acta Odontol. Scand. 68(4):228-231(2010)
- Ban, J.Y., et al. Life Sci. 86 (19-20), 756-759 (2010) :
- Deng, Y., et al. Oncol. Rep. 23(1):69-78(2010)
- Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.
56547
Matrix metalloproteinase-26
MMP26
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Q9NRE1
13629493
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Cell Cycle,Signal Transduction
Q9NRE1
Optimal dilutions for each application to be determined by the researcher.