Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
5'-AMP-activated protein kinase subunit gamma-3, AMPK gamma3, AMPK subunit gamma-3, PRKAG3, AMPKG3
For WB starting dilution is: 1:1000
The protein encoded by this gene is a regulatory subunit
of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer
consisting of an alpha catalytic subunit, and non-catalytic beta
and gamma subunits. AMPK is an important energy-sensing enzyme that
monitors cellular energy status. In response to cellular metabolic
stresses, AMPK is activated, and thus phosphorylates and
inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy
beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in
regulating de novo biosynthesis of fatty acid and cholesterol. This
subunit is one of the gamma regulatory subunits of AMPK. It is
dominantly expressed in skeletal muscle. Studies of the pig
counterpart suggest that this subunit may play a key role in the
regulation of energy metabolism in skeletal muscle. [provided by
RefSeq].
- Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010)
- Jassim, G., et al. Pharmacopsychiatry (2010) In press :
- Crawford, S.A., et al. Diabetologia 53(9):1986-1997(2010)
- Ramanathan, L., et al. Protein Expr. Purif. 70(1):13-22(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
This PRKAG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-454 amino acids from the C-terminal region of human PRKAG3.
53632
5'-AMP-activated protein kinase subunit gamma-3
PRKAG3
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Q9UGI9
85681287
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cancer,Obesity,Signal Transduction
Q9UGI9
Optimal dilutions for each application to be determined by the researcher.