ProSci

NEK8 Antibody

Product Code:
 
PSI-62-656
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Antibody is used in Western blot to detect NEK8 in A2058 cell lysate.
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Antibody is used in Western blot to detect NEK8 in A2058 cell lysate.

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PSI-62-656-400ul400ul£626.00
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Further Information

Additional Names:
Serine/threonine-protein kinase Nek8, Never in mitosis A-related kinase 8, NimA-related protein kinase 8, Nima-related protein kinase 12a, NEK8, JCK, NEK12A
Application Note:
For WB starting dilution is: 1:1000
Background:
NEK8 is a member of the serine/threionine protein kinase family related to NIMA (never in mitosis, gene A) of Aspergillus nidulans. The encoded protein may play a role in cell cycle progression from G2 to M phase. Mutations in the related mouse gene are associated with a disease phenotype that closely parallels the juvenile autosomal recessive form of polycystic kidney disease in humans.
Background References:
  • Valkova,N. et al. Mol. Cell Proteomics(7), 1009-1018 (2005)
  • Bowers,A.J. et al. Gene 328, 135-142 (2004)
  • Holland,P.M. et al. J. Biol. Chem. 277 (18), 16229-16240 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This NEK8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-95 amino acids from the N-terminal region of human NEK8.
NCBI Gene ID #:
284086
NCBI Official Name:
Serine/threonine-protein kinase Nek8
NCBI Official Symbol:
NEK8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
75 kDa
Protein Accession #:
Q86SG6
Protein GI Number:
34098463
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
Q86SG6
User NOte:
Optimal dilutions for each application to be determined by the researcher.