Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
No additional charges, what you see is what you pay! *
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available!
Contact us to find what you can save.
This product comes from:
United States.
Typical lead time:
14-21 working days.
Contact us for more accurate information.
- Further Information
- Documents
- Show All
Further Information
NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1, APPBP1
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for cell cycle progression through the S/M checkpoint.
- Chen,Y., J. Cell Biol. 163 (1), 27-33 (2003)
- Chen,Y., J. Neurochem. 85 (3), 801-809 (2003)
- Walden,H., Nature 422 (6929), 330-334 (2003)
- Chow,N., J. Biol. Chem. 271 (19), 11339-11346 (1996)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Monkey, Mouse, Rat
This NAE1 (APPBP1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 430-459 amino acids from the C-terminal region of human NAE1 (APPBP1).
8883
NEDD8-activating enzyme E1 regulatory subunit
NAE1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Q13564
50400302
This antibody is purified through a protein G column, followed by dialysis against PBS.
Cell Cycle
Q13564
Optimal dilutions for each application to be determined by the researcher.