Further Information
Casein kinase I isoform delta, CKI-delta, CKId, Tau-protein kinase CSNK1D, CSNK1D, HCKID
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The casein kinase 1 (CK1) group consists of 12 kinases including CK1, TTBK (tau tubulin kinase), and VRK (vaccinia-related kinase) families.
The receptor guanylate cyclase (RGC) group consists of 5 kinases similar in domain sequence to TKs (ANP, CYG).
- Sillibourne, J.E., et al., J. Mol. Biol. 322(4):785-797 (2002).
- Rivers, A., et al., J. Biol. Chem. 273(26):15980-15984 (1998).
- Kusuda, J., et al., Genomics 32(1):140-143 (1996).
- Fish, K.J., et al., J. Biol. Chem. 270(25):14875-14883 (1995).
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
This CSNK1D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-352 amino acids from the C-terminal region of human CSNK1D.
1453
Casein kinase I isoform delta
CSNK1D
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
P48730
27923980
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Cell Cycle,Neuroscience,Signal Transduction
P48730
Optimal dilutions for each application to be determined by the researcher.