Further Information
Mitochondrial ubiquitin ligase activator of NFKB 1, 632-, E3 SUMO-protein ligase MUL1, E3 ubiquitin-protein ligase MUL1, Growth inhibition and death E3 ligase, Mitochondrial-anchored protein ligase, MAPL, Putative NF-kappa-B-activating protein 266, RING finger protein 218, MUL1, C1orf166, GIDE, MAPL, MULAN, RNF218
For WB starting dilution is: 1:1000
E3 ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
- Laure, L., et al. FEBS J. 277(20):4322-4337(2010)
- Braschi, E., et al. EMBO Rep. 10(7):748-754(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Zhang, B., et al. Cell Res. 18(9):900-910(2008)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Monkey
This MUL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the C-terminal region of human MUL1.
79594
Mitochondrial ubiquitin ligase activator of NFKB 1
MUL1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Q969V5
74760689
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Obesity
Q969V5
Optimal dilutions for each application to be determined by the researcher.