Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, CAAX farnesyltransferase subunit alpha, FTase-alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl-geranyltransferase subunit alpha, GGTase-I-alpha, FNTA
For WB starting dilution is: 1:1000
Prenyltransferases can attach either a farnesyl group or a
geranylgeranyl group in thioether linkage to the cysteine residue
of proteins with a C-terminal CAAX box. CAAX
geranylgeranyltransferase and CAAX farnesyltransferase are
heterodimers that share the same alpha subunit but have different
beta subunits. This gene encodes the alpha subunit of these
transferases. Alternative splicing results in multiple transcript
variants. Related pseudogenes have been identified on chromosomes
11 and 13.
- Lipkin, S.M., et al. Cancer Prev Res (Phila Pa) 3(5):597-603(2010)
- Fontaine-Bisson, B., et al. J. Mol. Med. 88(2):193-201(2010)
- Zhou, J., et al. J. Biol. Chem. 284(15):9648-9655(2009)
- Veluthakal, R., et al. Diabetes 56(1):204-210(2007)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Mouse, Rat
This FNTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human FNTA.
2339
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
FNTA
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
P49354
1346694
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Signal Transduction
P49354
Optimal dilutions for each application to be determined by the researcher.