Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Application:
Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
Leukocyte immunoglobulin-like receptor subfamily B member 4, CD85 antigen-like family member K, Immunoglobulin-like transcript 3, ILT-3, Leukocyte immunoglobulin-like receptor 5, LIR-5, Monocyte inhibitory receptor HM18, CD85k, LILRB4, ILT3, LIR5
For WB starting dilution is: 1:1000
This gene is a member of the leukocyte immunoglobulin-like
receptor (LIR) family, which is found in a gene cluster at
chromosomal region 19q13.4. The encoded protein belongs to the
subfamily B class of LIR receptors which contain two or four
extracellular immunoglobulin domains, a transmembrane domain, and
two to four cytoplasmic immunoreceptor tyrosine-based inhibitory
motifs (ITIMs). The receptor is expressed on immune cells where it
binds to MHC class I molecules on antigen-presenting cells and
transduces a negative signal that inhibits stimulation of an immune
response. The receptor can also function in antigen capture and
presentation. It is thought to control inflammatory responses and
cytotoxicity to help focus the immune response and limit
autoreactivity. Multiple transcript variants encoding different
isoforms have been found for this gene.
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Lu, H.K., et al. J. Biol. Chem. 284(50):34839-34848(2009)
- Jones, D.C., et al. Eur. J. Immunol. 39(11):3195-3206(2009)
- Brenk, M., et al. J. Immunol. 183(1):145-154(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This LILRB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human LILRB4.
11006
Leukocyte immunoglobulin-like receptor subfamily B member 4
LILRB4
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Q8NHJ6
322510117
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunology
Q8NHJ6
Optimal dilutions for each application to be determined by the researcher.