Further Information
Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IF starting dilution is: 1:10~50
This gene encodes a precursor protein consisting of
arginine vasopressin and two associated proteins, neurophysin 2 and
a glycopeptide, copeptin. Arginine vasopressin is a posterior
pituitary hormone which is synthesized in the supraoptic nucleus
and paraventricular nucleus of the hypothalamus. Along with its
carrier protein, neurophysin 2, it is packaged into neurosecretory
vesicles and transported axonally to the nerve endings in the
neurohypophysis where it is either stored or secreted into the
bloodstream. The precursor is thought to be activated while it is
being transported along the axon to the posterior pituitary.
Arginine vasopressin acts as a growth factor by enhancing pH
regulation through acid-base transport systems. It has a direct
antidiuretic action on the kidney, and also causes vasoconstriction
of the peripheral vessels. This hormone can contract smooth muscle
during parturition and lactation. It is also involved in cognition,
tolerance, adaptation and complex sexual and maternal behaviour, as
well as in the regulation of water excretion and cardiovascular
functions.
- Abu Libdeh, A., et al. Eur. J. Endocrinol. 162(2):221-226(2010)
- Cirillo, M. Kidney Int. 77(1):5-6(2010)
- Meijer, E., et al. Kidney Int. 77(1):29-36(2010)
- Birk, J., et al. J. Cell. Sci. 122 (PT 21), 3994-4002 (2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This AVP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human AVP.
551
Vasopressin-neurophysin 2-copeptin
AVP
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
P01185
128083
This antibody is purified through a protein A column, followed by peptide affinity purification.
Neuroscience,Signal Transduction
P01185
Optimal dilutions for each application to be determined by the researcher.