Further Information
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, SERCA2, SR Ca(2+)-ATPase 2, Calcium pump 2, Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase, ATP2A2, ATP2B
For WB starting dilution is: 1:1000
This gene encodes one of the SERCA Ca(2+)-ATPases, which
are intracellular pumps located in the sarcoplasmic or endoplasmic
reticula of muscle cells. This enzyme catalyzes the hydrolysis of
ATP coupled with the translocation of calcium from the cytosol into
the sarcoplasmic reticulum lumen, and is involved in regulation of
the contraction/relaxation cycle. Mutations in this gene cause
Darier-White disease, also known as keratosis follicularis, an
autosomal dominant skin disorder characterized by loss of adhesion
between epidermal cells and abnormal keratinization. Alternative
splicing results in multiple transcript variants encoding different
isoforms.
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Tuusa, J.T., et al. FEBS J. 277(13):2815-2829(2010)
- Godic, A., et al. EurDermatol 20(3):271-275(2010)
- Godic, A., et al. J. Am. Acad. Dermatol. 62(5):819-823(2010)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This ATP2A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the Central region of human ATP2A2.
488
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
ATP2A2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
115 kDa
P16615
114312
This antibody is purified through a protein A column, followed by peptide affinity purification.
Obesity,Signal Transduction
P16615
Optimal dilutions for each application to be determined by the researcher.