ProSci

SUB1 Antibody

Product Code:
 
PSI-60-725
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis in K562 cell line lysates (35ug/lane).

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PSI-60-725-400ul400ul£626.00
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Further Information

Additional Names:
Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14, SUB1, PC4, RPO2TC1
Application Note:
For WB starting dilution is: 1:1000
Background:
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
Background References:
  • Das, C., et al. J. Mol. Biol. 397(1):1-12(2010)
  • Rajagopalan, S., et al. J. Biol. Chem. 284(32):21728-21737(2009)
  • Mortusewicz, O., et al. J. Cell Biol. 183(5):769-776(2008)
  • Batta, K., et al. Mol. Cell. Biol. 27(21):7603-7614(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This SUB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-47 amino acids from the Central region of human SUB1.
NCBI Gene ID #:
10923
NCBI Official Name:
Activated RNA polymerase II transcriptional coactivator p15
NCBI Official Symbol:
SUB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
14 kDa
Protein Accession #:
P53999
Protein GI Number:
1709514
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P53999
User NOte:
Optimal dilutions for each application to be determined by the researcher.