ProSci

NDST3 Antibody

Product Code:
 
PSI-59-371
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Western blot analysis in HL-60 cell line lysates (35ug/lane).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).

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PSI-59-371-400ul400ul£626.00
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Further Information

Additional Names:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3, Glucosaminyl N-deacetylase/N-sulfotransferase 3, NDST-3, hNDST-3, N-heparan sulfate sulfotransferase 3, N-HSST 3, Heparan sulfate N-deacetylase 3, 3---, Heparan sulfate N-sulfotransferase 3, 282-, NDST3, HSST3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. This monomeric bifunctional enzyme catalyzes the N-deacetylation and N-sulfation of N-acetylglucosamine residues in heparan sulfate and heparin, which are the initial chemical modifications required for the biosynthesis of the functional oligosaccharide sequences that define the specific ligand binding activities of heparan sulfate and heparin.
Background References:
  • Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
  • Krenn, E.C., et al. Biochem. Biophys. Res. Commun. 375(3):297-302(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This NDST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 809-836 amino acids from the C-terminal region of human NDST3.
NCBI Gene ID #:
9348
NCBI Official Name:
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3
NCBI Official Symbol:
NDST3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
101 kDa
Protein Accession #:
O95803
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O95803
User NOte:
Optimal dilutions for each application to be determined by the researcher.