ProSci

KCTD10 Antibody

Product Code:
 
PSI-57-028
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
Rabbit Ig
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
 
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1 / 3
Western blot analysis in Jurkat cell line lysates (35ug/lane).
2 / 3
KCTD10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
KCTD10 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

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PSI-57-028-400ul400ul£626.00
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Further Information

Additional Names:
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, hBACURD3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization domain-containing protein 10, KCTD10, ULR061
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex. The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
Background References:
  • Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Junyent, M., et al. Am. J. Clin. Nutr. 90(3):686-694(2009)
  • Wang, Y., et al. J. Cell. Biochem. 106(3):409-413(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KCTD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the C-terminal region of human KCTD10.
NCBI Gene ID #:
83892
NCBI Official Name:
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3
NCBI Official Symbol:
KCTD10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q9H3F6
Protein GI Number:
74733570
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H3F6
User NOte:
Optimal dilutions for each application to be determined by the researcher.