Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
F-box/WD repeat-containing protein 8, F-box and WD-40 domain-containing protein 8, F-box only protein 29, FBXW8, FBW6, FBW8, FBX29, FBXO29, FBXW6
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
This gene encodes a member of the F-box protein family,
members of which are characterized by an approximately 40 amino
acid motif, the F-box. The F-box proteins constitute one of the
four subunits of ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into three classes:
Fbws containing WD-40 domains, Fbls containing leucine-rich
repeats, and Fbxs containing either different protein-protein
interaction modules or no recognizable motifs. The protein encoded
by this gene contains a WD-40 domain, in addition to an F-box
motif, so it belongs to the Fbw class. Alternatively spliced
transcript variants encoding distinct isoforms have been identified
for this gene.
- Tsutsumi, T., et al. Mol. Cell. Biol. 28(2):743-751(2008)
- Koch, H.B., et al. Cell Cycle 6(2):205-217(2007)
- Okabe, H., et al. PLoS ONE 1, E128 (2006) :
- Watanabe, N., et al. Proc. Natl. Acad. Sci. U.S.A. 101(13):4419-4424(2004)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
This FBXW8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the Central region of human FBXW8.
26259
F-box/WD repeat-containing protein 8
FBXW8
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Q8N3Y1
296434513
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle
Q8N3Y1
Optimal dilutions for each application to be determined by the researcher.