Antibody Isotype:
Rabbit Ig
Antibody Clonality:
Polyclonal
Applications:- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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- Further Information
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Further Information
2-hydroxyacylsphingosine 1-beta-galactosyltransferase, Ceramide UDP-galactosyltransferase, Cerebroside synthase, UDP-galactose-ceramide galactosyltransferase, UGT8, CGT, UGT4
For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50
Galactocerebrosides are abundant sphingolipids of the
myelin membrane of the central nervous system and peripheral
nervous system and are also present in small amounts in kidney. The
key enzymatic step in the biosynthesis of galactocerebrosides
consists of the transfer of galactose to ceramide catalyzed by
UDP-galactose ceramide galactosyltransferase (CGT, EC 2.4.1.45).
The enzyme encoded by the CGT gene is the first involved in complex
lipid biosynthesis in the myelinating oligodendrocyte.[supplied by
OMIM].
- Dziecedil Giel, P., et al. Br. J. Cancer 103(4):524-531(2010)
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Ross, C.J., et al. Nat. Genet. 41(12):1345-1349(2009)
- Ruckhaberle, E., et al. J. Cancer Res. Clin. Oncol. 135(8):1005-1013(2009)
Supplied in PBS with 0.09% (W/V) sodium azide.
batch dependent
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Predicted species reactivity based on immunogen sequence: Rat
This UGT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-393 amino acids from the Central region of human UGT8.
7368
2-hydroxyacylsphingosine 1-beta-galactosyltransferase
UGT8
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
61 kDa
Q16880
296434442
This antibody is purified through a protein A column, followed by peptide affinity purification.
Cell Cycle,Obesity,Signal Transduction
Q16880
Optimal dilutions for each application to be determined by the researcher.